Benzyl-PEG9-acid

Benzyl-PEG9-acid 是一種 PROTAC linker，屬于 PEG 類(lèi)?？捎糜诤铣?nbsp;PROTAC 分子。

生物活性

Benzyl-PEG9-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs^[1].

IC₅₀ & Target

PEGs

體外研究(In Vitro)

PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins^[1].

分子量:532.62

Formula:C₂₆H₄₄O₁₁

運(yùn)輸條件:Room temperature in continental US; may vary elsewhere.

儲(chǔ)存方式:Please store the product under the recommended conditions in the Certificate of Analysis.

參考文獻(xiàn)

• [1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562  [Content Brief]